产品货号：
Z16607
中文名称：
FKBP8抗体
英文名称：
Anti-FKBP8 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FKBP8 Antibody |
| 指标别名 | 38kDa FK506 binding protein;38kDa FKBP;FK506 binding protein 8;FK506 binding protein 8;38kDa;FKBP 38;FKBP 8;FKBP38;FKBP8;FKBPr38;hFKBP38;PPIase FKBP8;Rotamase |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB |
| 基因名称 | FKBP8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human FKBP8 protein. |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This product was protein A purified from monospecific antiserum by immunoaffinity chromatography using protein A coupled to agarose beads.?This antibody is specific for human FKBP8 protein.A BLAST analysis was used to suggest partial cross-reactivity with FKBP8 from mouse and rat sources based on~93% homology with the immunizing sequence.Cross-reactivity with FKBP8 from other sources has not been determined. |
| 浓度 | 2.3mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | FKBP8 (also known as FK506-binding protein 38) is a member of the immunophilin family that has been implicated to play an important role in apoptosis through its involvement in the mechanism that targets Bcl-2 and Bcl-xL to the outer mitochondrial membrane (OMM).Suppression of endogenous FKBP8 by RNAi or transfection of a mutant FKBP8 missing the transmembrane domain necessary for mitochondrial insertion,resulted in the translocation of Bcl-2 and Bcl-xL from the OMM to the cytosol.It has also been suggested that FKBP8 may play a role in the regulation of apoptosis.Anti-FKBP8 Antibody is useful for researchers interested in HIV,Cancer,and Metabolism of protein research. |
| Uniprot ID | Q14318 |
| 推荐稀释比 | ELISA:1:25,000 WB:1:500 - 1:2,000 |
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